PCOD is Polycystic Ovarian Disease, it is also called as PCOS i.e. Polycystic Ovarian Syndrome. It is multifactorial in origin. Today’s life style is predisposing this condition, leading to its increasing incidence. Physical inactivity, high calorie food, long working hours, insufficient sleep, demanding work pattern, anxious mind,
overactive cerebral function are disturbing the HPO axis.
Pathophysiology of PCOD
The release of GnRh from hypothalamus, which controls FSH & LH in a particular pattern, gets disturbed. This leads to low levels of FSH & high levels of LH. Low levels of FSH lead to anovulation leading to infertility. High levels of LH, lead to excessive secretion of androgens (male hormones) from Theca cells of ovaries. High levels Androgens are responsible for acne & hirsutism. Obesity is excessive adipose tissue (fatty) in body. This converts one form of female hormone (estrone) from androstenedione. Its‟ persistent high level (not cyclic) leads to low levels of FSH, from pituitary. Constant anxiety and cerebral over function leads to hypothalamic dysfunction